Mass spec is poised to fulfill its potential in the QC lab, say researchers who claim that a new intact protein analysis method overcomes challenges that have up to now limited adoption. Growing ...

A worldwide study involving 12 research groups has confirmed that capillary zone electrophoresis combined with mass ...

Researchers have detailed PEPPI-MS, an experimental protocol combining high-resolution protein fractionation using SDS-polyacrylamide gel electrophoresis (SDS-PAGE) with the latest mass spectrometry ...

Protein drugs feature significant advantages over small molecule therapeutics, including low toxicity, high specificity, and development speed. However, the quality control requirements are ...

Nanobodies are single-domain antibodies derived from heavy-chain-only antibodies (HcAbs) commonly found in camelids, consisting solely of the variable, antigen-binding domain. Their small size affords ...

Elucidating information about proteins present in biological samples is vital for scientists working in the field of life sciences. Whilst qualitative data can tell us which proteins are present in a ...

The process of protein identification typically begins with a bottom-up approach, where proteins are enzymatically digested—most commonly with trypsin—into smaller peptides. These peptides are ...