Traditionally, scientists have used 2D cell cultures as in vitro models in drug screening studies due to their simplicity and scalability. However, 2D cell models do not recapitulate the complexity of ...

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part ...

Bioengineers have developed a platform that accurately replicates conditions cancer cells encounter while traveling through ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

This article is based on a poster originally authored by D. Cole and N. Bevan. 3D models, including spheroids and organoids, are increasingly used to investigate disease and development. Developing, ...

3D-printed lungs made with living cells could help to improve lung disease prevention and treatment—and potentially one day offer a lab-grown option for use in organ transplants. University of ...

Researchers translated experimental data into Minecraft files to recreate 3D images in a more accessible setting. My group studies the minimum requirements for cells to live. As part of one project, ...

Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...

New confocal fluorescence imaging minimizes photobleaching and phototoxicity effects, capturing clear images of live 3D culture Industry-leading throughput enables real-time analysis of up to six ...